USA TODAY Sports’ Week 5 NFL picks: Do Colts or Browns get to four wins first?

The NFL embarks on the second quarter of its season in Week 5, hoping COVID-19 doesn't cause further havoc to the league's schedule. However that seems unlikely with Sunday's Bills-Titans game in serious jeopardy, and no assurance Broncos-Patriots will be safe enough to play as scheduled, either.

But, assuming the pandemic doesn't jeopardize any more matchups, there are a few worth sinking your teeth into – including Buffalo and Tennessee, which will be the only pairing of undefeated clubs this week if the game is actually played. 

Thursday night's Buccaneers-Bears showcase features two 3-1 squads. Same goes for the Colts' visit to Cleveland on Sunday, perhaps the most compelling contest on the menu and one that actually didn't create consensus among our panel of experts.

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